The Farber Lab

at the University of Virginia

The Farber lab uses Systems Genetics in the mouse to identify novel genes and gene networks involved in bone development with an emphasis on factors affecting the function of bone-forming osteoblasts.

Systems Genetics: Our Approach

  • Systems Genetics

    Systems Genetics of Complex Skeletal Phenotypes

    Systems genetics seeks to understand how genetic information is integrated, organized and transmitted through cellular networks to impact cellular function/behavior. Much of our work in the lab uses systems genetics approaches that integrate genetic and transcriptome data to identify individual genes and gene networks influencing complex skeletal phenotypes.

    Example Papers: Mesner et al. Bicc1, Farber et al. Asxl2, Calabrese et al. Plos Genetics.

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Charles Farber