GWAS have identified dozens of loci for bone mineral density (BMD). The next step is to use these data to identify the genetic variants and genes responsible for the genetic effects.

Single Cell

Skeletal development and maintenance is controlled by numerous cell-types. Historically, genomic studies of bone cells have been challenging due to difficulties in isolating homogenous cell-types from marrow or bone. Recently, this has begun to change with the emergence of single cell technologies